Decoy for microRNAs
نویسندگان
چکیده
منابع مشابه
MicroRNAs: From Decay to Decoy
MicroRNAs interact with Argonaute proteins to guide posttranscriptional gene silencing. Eiring et al. (2010) now show that miR-328 has a second function, acting as a decoy by binding to hnRNP E2 and lifting its translational repression of an mRNA involved in myeloid cell differentiation.
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RNA Binding Proteins Anna M. Eiring *1 Abstract Altered microRNA (miRNA) expression contributes to aberrant post-transcriptional gene regulation in several types of cancers; however, their role in the progression of chronic myeloid leukemia (CML) from chronic phase (CML-CP) to blast crisis (CML-BC) is still largely unknown. To gain further insight into the role of miRNAs in CML disease progress...
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ژورنال
عنوان ژورنال: Nature
سال: 2010
ISSN: 0028-0836,1476-4687
DOI: 10.1038/4651016a